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Texas Tech University School Of Pharmacy

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I am a Pharmacy student @Texas Tech University School of Pharmacy and was wondering if anyone knows the exact mechanism for the interaction of yohimbine and red wine.

Yohimbine is primarily an alpha-2 adrenergic BLOCKER. According to "Facts and Comparisons," its effects should be to lower blood pressure. However no studies exist to quantify this and some reports indicate that it may increase blood pressure. My own anecdotal experience in two patients showed increased BP, tachycardia, skin flushing and a helluva headache. Both decided it wasn't worth it!

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